Babylon 5 (7) 
Mongoose Publishing says it's "The greatest science fiction adventure ever comes to roleplaying as it has never been seen before. The Babylon 5 Roleplaying Game is the single greatest information resource available for the award-winning television series."

Battlestar Galactica (2) 
Whether the campy 80's version or the gritty reimagined, find your battlestar, join the crew and run from the Cylons in these games.

Buffy The Vampire Slayer (6) 
So ya wanna be a Slayer? Find RPGs relating to all things Vampire Slayer here.

Charmed (4) 
Whether you want to play one of the Charmed Ones, or whole new characters, look here for roleplaying games based on the Charmed TV series.

Dungeons and Dragons (21) 
Dungeons & Dragons is a traditional fantasy RPG published by Wizards of the Coast. The original Dungeons & Dragons, first published in 1974, is generally regarded as the beginning of modern role-playing games.

Farscape (5) 
From the vast reaches of the Uncharted Territories, Alderac Entertainment Group brings us the Farscape role-playing game!

Final Fantasy (10) 
Light Warriors, defeat the Elemental Fiends (or just hang out with them) in these Final Fantasy games.

Harry Potter (58) 
A selection of games based on Harry Potter, using a variety of rules and methods. If you're looking to play HP, here you go.

Lord of the Rings (2) 
Roleplaying and resources for the granddaddy of RPGS - Tolkien's Lord of the Rings!

Naruto (5) 
Naruto is a manga by Masashi Kishimoto with an anime TV series adaptation. Its main character, Naruto Uzumaki, is a loud, hyperactive, adolescent ninja who constantly searches for approval and recognition, as well as to become Hokage, acknowledged as the leader and strongest of all ninja in the village.

Pern (3) 
Pern is the home of Dragons, their riders, and various other people as depicted in Anne McCaffrey's Dragonriders of Pern series and related books.

Serenity - Firefly (4) 
Games based on Joss Wheden's Firefly series and/or Serenity movie.

Star Trek (40) 
Star Trek began as a unique television series created by Gene Roddenberry. It depicts a future in which humanity has overcome such traditional frailities as racism, poverty, intolerance, warfare and religious strife, and has united with other intelligent species in the galaxy.

Star Wars (32) 
Prepare to clash with Trade Federation battle droids, droid starfighters, battle tanks, and numerous other enemies in the popular Star Wars setting.

Stargate (6) 
Jumping through wormholes to new world, discovering new civilizations, fighting the goa'uld and worse - try a Stargate RPG.

The Matrix (3) 
If you loved the movies, and are ready to be brought out, look for a game here.

X-Men (20) 
The X-Men are mutants who, as a result of a sudden leap in evolution, are born with superhuman abilities which generally manifest themselves at puberty. Many ordinary humans harbor an intense fear and/or distrust of mutants, who are regarded by a number of scientists as the next step in human evolution. The tensions are exacerbated by mutants who use their powers for criminal ends.